Neural Regeneration Research

REVIEW
Year
: 2022  |  Volume : 17  |  Issue : 8  |  Page : 1640--1644

Calorie restriction or dietary restriction: how far they can protect the brain against neurodegenerative diseases?


Tayana Silva de Carvalho 
 Herz- und Diabeteszentrum NRW (HDZ NRW), Bad Oeynhausen, Germany

Correspondence Address:
Tayana Silva de Carvalho
Herz- und Diabeteszentrum NRW (HDZ NRW), Bad Oeynhausen
Germany

Finding the correct nutritional intervention is one of the biggest challenges in treating patients with neurodegenerative diseases. In general, these patients develop strong metabolic alterations, resulting in lower treatment efficacy and higher mortality rates. However, there are still many open questions regarding the effectiveness of dietary interventions in neurodiseases. Some studies have shown that a reduction in calorie intake activates key pathways that might be important for preventing or slowing down the progression of such diseases. However, it is still unclear whether these neuroprotective effects are associated with an overall reduction in calories (hypocaloric diet) or a specific nutrient restriction (diet restriction). Therefore, here we discuss how commonly or differently hypocaloric and restricted diets modulate signaling pathways and how these changes can protect the brain against neurodegenerative diseases.


How to cite this article:
de Carvalho TS. Calorie restriction or dietary restriction: how far they can protect the brain against neurodegenerative diseases?.Neural Regen Res 2022;17:1640-1644


How to cite this URL:
de Carvalho TS. Calorie restriction or dietary restriction: how far they can protect the brain against neurodegenerative diseases?. Neural Regen Res [serial online] 2022 [cited 2022 Jan 17 ];17:1640-1644
Available from: http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=8;spage=1640;epage=1644;aulast=de;type=0