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  Indian J Med Microbiol
 

Figure 1: The lysosome-centered theory. Schematic representation of the main lysosomal functions within the cell, where the tiny organelle lysosome plays a major role in membrane repair, autophagosome formation, TFEB activation through Ca2+-releasing activity of TRPML1 channel, endoplasmic reticulum refilling and lysosomes-mitochondria crosstalk. TFEB: Transcription factor EB.

<b>Figure 1: The lysosome-centered theory.</b>
Schematic representation of the main lysosomal functions within the cell, where the tiny organelle lysosome plays a major role in membrane repair, autophagosome formation, TFEB activation through Ca<sup>2+</sup>-releasing activity of TRPML1 channel, endoplasmic reticulum refilling and lysosomes-mitochondria crosstalk. TFEB: Transcription factor EB.