Figure 8: Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of differentially expressed mRNAs in cerebral tissue of IR rats with ISP and RIP treatment. (A–D) Twenty pathways that were most significantly associated with upregulated long noncoding RNAs (lncRNAs) in each group comparison (IR vs. sham, ISP vs. IR, RIP vs. IR, and ISP vs. RIP groups, respectively). (E–H) Twenty pathways most associated with downregulated lncRNAs in each group comparison (IR vs. sham, ISP vs. IR, RIP vs. IR, and ISP vs. RIP groups, respectively). The q-value is the P-value corrected after multiple hypothesis tests. The q-value ranges from 0 to 1, with values closer to 0 indicating increased enrichment significance. IR: Ischemia/reperfusion; ISP: in situ ischemic postconditioning; RIP: remote ischemic postconditioning.