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  Indian J Med Microbiol
 

Figure 1: Cellular sources for transplantation to treat amyotrophic lateral sclerosis. Three major steps are included in the process of cell transplantation—cell extraction, differentiation and transplantation. Neural progenitor cells (NPCs) can be either isolated from fetuses or from other stem cells such as embryonic stem cells (ESCs, derived from the inner cell mass of blastocysts) or induced pluripotent stem cells (iPSCs, reprogrammed from peripheral blood mononuclear cells (PBMCs)). The NPCs can be directly used for transplantation or following one more step that specifies the cells to lineage-specific precursor cells, such as glial-restricted precursors (GRPs) and neuronal precursor cells.

<b>Figure 1: Cellular sources for transplantation to treat amyotrophic lateral sclerosis.</b>
Three major steps are included in the process of cell transplantation—cell extraction, differentiation and transplantation. Neural progenitor cells (NPCs) can be either isolated from fetuses or from other stem cells such as embryonic stem cells (ESCs, derived from the inner cell mass of blastocysts) or induced pluripotent stem cells (iPSCs, reprogrammed from peripheral blood mononuclear cells (PBMCs)). The NPCs can be directly used for transplantation or following one more step that specifies the cells to lineage-specific precursor cells, such as glial-restricted precursors (GRPs) and neuronal precursor cells.