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  Indian J Med Microbiol
 

Figure 3: Transplanted MNPs differentiate into motor neurons and extend their axons along motor axon tracts. (A, B) Transplanted human induced pluripotent stem cells (iPSCs)-derived motor neuron progenitors (MNPs) labeled for human nuclei (hNu) and GFP survived in the mid-cervical spinal cord ventral horn in immunodeficient rats (A) and differentiated into choline acetyl transferae (ChAT+) motor neurons 3 months post transplantation (B). (C) Transplant-derived neurons extended their axons along motor axonal tracts in the ventral spinal cord. Scale bars: 200 μm in A, 18 μm in B, and 68 μm in C. Unpublished data.

<b>Figure 3: Transplanted MNPs differentiate into motor neurons and extend their axons along motor axon tracts.</b>
(A, B) Transplanted human induced pluripotent stem cells (iPSCs)-derived motor neuron progenitors (MNPs) labeled for human nuclei (hNu) and GFP survived in the mid-cervical spinal cord ventral horn in immunodeficient rats (A) and differentiated into choline acetyl transferae (ChAT<sup>+</sup>) motor neurons 3 months post transplantation (B). (C) Transplant-derived neurons extended their axons along motor axonal tracts in the ventral spinal cord. Scale bars: 200 μm in A, 18 μm in B, and 68 μm in C. Unpublished data.